Video: Israel Kills Hamas Honcho

Video: Israel Kills Hamas Honcho

The video description:

On Nov. 11, 2012, the IDF targeted Ahmed Jabri, the head of Hamas' military wing, in the Gaza Strip. Jabri was a senior Hamas operative who served in the upper echelon of the Hamas' command and was directly responsible for executing terror attacks against Israel in the past.
Israel has claimed Jabri was linked to the kidnapping of IDF soldier Gilad Shalit. Israel is bracing for terrorist attacks, and may conduct further actions in Gaza to either forestall the attacks, or avenge them. via @@NoahPollak.
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Source: http://minx.cc/?post=334913

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Camera for iPhone and iPad updates with flash for front-facing camera and more

The popular photography app Camera+ by tap tap tap has been updated with several new features, the most interesting one being the addition of a "flash" to the front-facing camera. Obviously, this flash isn't a real flash since that is a hardware piece, but Camera+ now flashes a bright white background onto the screen when taking a photo to simulate using a flash. This is similar to the approach that Apple takes with Photo Booth on the Mac.

Another notable feature added to Camera+ is a horizon level that ensures you don't take a crooked photo. Instead of a complicated looking meter that some apps use, tap tap tap took a new approach by replacing one of the segments of the gridlines with a bolder tilting segment. When the segment lines up with your gridlines, then you know your photo is straight.

Camera+ has also added a Live Exposure feature that should draw the attention of iPhoneographers who want more control. Now you can see how the changes to exposure parameters like ISO and shutter speed change in real-time. This will be a great time-saver for many.

You may not have ever realized it, but when using the camera on the iPhone 5, the viewfinder actually crops a little bit of what your camera actually sees and what you'll get. Camera+ has fixed this problem and set up the interface in a way that ensures there is absolutely no viewfinder cropping. What you see is what you shoot.

All of these features to Camera+ are quite excellent and I look forward to spending more time with the app over the coming weeks.

Both the iPhone and iPad versions of Camera+ are on sale, so if you're interested in picking this one up, do it now! After you do, we'd love to see your photos in the iMore Photography forum!

$0.99 for iPhone - Download Now

$0.99 for iPad - Download Now

Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/n5mKp5bN5N0/story01.htm

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90% A Royal Affair

All Critics (49) | Top Critics (13) | Fresh (44) | Rotten (5)

It does a fine job of dramatizing the pure power of ideas and the attraction of like minds. And what happens when those ideas, and that attraction, runs counter to the pleasures of the most powerful man in the land.

"A Royal Affair" is basically a good-looking set of historical Cliffs Notes.

This highly polished costume drama is exceptionally well-made and a model of intelligent restraint, but it is also unapologetically earnest and a bit on the bloodless side.

With its sumptuous settings, urgent romance and intellectual substance, A Royal Affair is a mind-opener crossed with a bodice-ripper.

Unfortunately it never fully comes to life.

While it's lavish and lush in all the expected costume-drama ways, A Royal Affair never bogs down in period detail.

Epic and intriguing, it's a cautionary tale that emerges as one of the best foreign films of the year.

It's a film about a society at a crossroads, with two competing visions of the future being hashed out against a backdrop of political intrigue. Sound familiar?

Hefty historical drama has some racy, violent moments.

Beautifully acted and lush look at a real-life court threesome in Denmark at the end of the 18th century indeed pleases.

Looks sumptuous and contains meaty, provocative ideas. It's a feast of a film, one that will send you scurrying for background on the real people behind this true story.

Director Nikolaj Arcel, who also co-wrote the screenplay, stages the action in a brisk, modern mode that makes 'A Royal Affair' easily digestible and satisfying.

...while Mads Mikkelsen has become an international star and has the sexier role here, it is Mikkel Boe F?lsgaard who really astonishes, always keeping us wondering if the King's madness is real or, at least in part, a tactic.

A richly conceived and compelling historical drama about two soulmates who try to rock the authorities and bring radical change to eighteenth century Denmark.

At least for a while, Arcel manages to animate the long-settled debate, at least until the inevitability of its resolution becomes too clear to overlook.

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Source: http://www.rottentomatoes.com/m/en_kongelig_affaere/

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Police: Arizona woman runs down husband with car for not voting

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Source: http://news.yahoo.com/arizona-woman-runs-down-husband-car-not-voting-045426220.html

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Kentucky Health News: State officials appear to be overstating ...

There's new criticism from Kentucky's doctors in an analysis of the state's four-month old prescription drug law, showing that a lot of what state officials have touted as the law's successes were already in the works before the law went into effect.

The Courier-Journal of Louisville reviewed state records after Gov. Steve Beshear released figures last month that showed the Kentucky Board of Medical Licensure had disciplined 33 physicians for violating professional prescription standards. Reporter Mike Wynn writes that he "found that 16 of the cases were resolved before the new law took effect on July 20, and 13 others involved investigations or actions that were well under way before the law?s implementation. The administration also reported last month that 18 of the 44 known pain-management clinics in Kentucky have closed or discontinued pain management services, including 10 after House Bill 1. Still, state records are unclear if all the clinics were suspected of illegal prescribing."

?They?ve taken a situation that required a scalpel to cut out the disease and instead they have used a machete,? Gregory Hood, governor of the Kentucky chapter of the American College of Physicians, told Wynn.

Beshear's announcement last month about the bill's almost overnight success also included crediting it for drops in prescriptions being written for pain killers, most notably for oxymorphone, which had a 38 percent falloff.? But, writes Wynn, "Critics of the law say that at least part of those declines are due to doctors denying needed prescriptions to patients because of problems with HB 1." Experts told the paper that oxymorphone, commonly prescribed as Opana, was not readily available in the market during the applicable period because of a reformulation by its manufacturer. (Read more)

Source: http://kyhealthnews.blogspot.com/2012/11/state-officials-appear-to-be.html

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Interrogating the "Gap" Between Law and Justice: East Timor's ...

Lia Kent. Human Rights Quarterly 34, no. 4 (2012): 1021-1044. - Abstract: War crimes trials are claimed to hold the capacity to contribute to a range of ambitious justice goals in post-conflict societies, such as the public recognition of victims' experiences, the promotion of respect for the rule of law, and the fostering of reconciliation. This article unsettles these claims through a case study of the UN-sponsored Serious Crimes Process in East Timor. It charts the practical and political constraints upon the Serious Crimes Process which undermined its ability to achieve its own goals. In addition, it draws on interviews with East Timorese survivors to demonstrate the difficulties faced by the Serious Crimes Process in fully meeting locally grounded demands for justice. This analysis illustrates the inherent limits of war crimes trials in responding to calls for justice, which transcend the possibilities of the criminal law.

ETLJB Editor's Note: Unfortunately, access to the full article is only available for payment. Search for the Human Rights Quarterly if you can afford to pay for this edition of the journal to read the full article. Hopefully, the Human Rights Quarterly will make this article available in East Timor's educational institutions free of charge.



Source: http://easttimorlegal.blogspot.com/2012/11/interrogating-gap-between-law-and.html

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New method of gene identification discovered

ScienceDaily (Nov. 11, 2012) ? Scientists studying the genes and proteins of human cells infected with a common cold virus have identified a new gene identification technique that could increase the genetic information we hold on animals by around 70 to 80 per cent. The findings, published in Nature Methods, could revolutionise our understanding of animal genetics and disease, and improve our knowledge of dangerous viruses such as SARS that jump the species barrier from animals to humans.

Modern advances in genome sequencing -- the process of determining the genetic information and variation controlling everything from our eye colour to our vulnerability to certain diseases -- has enabled scientists to uncover the genetic codes of a wide range of animals, plants and insects.

Until now, correctly identifying the genes and proteins hidden inside the genetic material of a newly sequenced species has been a monumental undertaking requiring the careful observation and cataloguing of vast amounts of data about the thousands of individual genes that make up any given animal, plant or insect.

Dr David Matthews, the study's lead author and a Senior Lecturer in Virology at the University of Bristol's School of Cellular and Molecular Medicine, said: "Gene identification is mainly led by computer programmes which search the genome for regions that look like genes already identified in other animals or humans. However, this type of analysis is not always effective."

The Bristol team has now discovered a more effective way of detecting the genetic information present in animals, plants and insects using cutting-edge analysis tools to directly observe the genes and all the proteins they make.

To prove their technique worked, the researchers conducted an experiment to see how good their process was at gene discovery. Human cells were infected with a well-understood common cold bug to mimic a newly discovered virus. These infected cells were then analysed using the technique as if they were cells from a newly sequenced organism infected with a newly discovered virus.

The resulting list of "discovered" genes and proteins, when compared to the genetic information already known about humans and cold virus, proved extremely successful and demonstrated the power of this method.

A similar analysis of hamster cells provided directly observed evidence for the existence of thousands of genes and proteins in hamsters in a single relatively inexpensive experiment. Direct evidence for the existence of almost all of theses genes and proteins in hamsters is not available in the 'official' lists of hamster genes and proteins.

Dr Matthews added: "These findings open up the potential to take powerful analysis tools currently used to study human diseases and apply them to study any animal, insect or even plants -- something previously either very challenging or simply not possible. This technique will also make it easier and much more efficient for scientists to study anything from farm animals and their diseases to insect pests that damage crops.

"In recent years, a number of dangerous new viruses have been transmitted from animals to humans including Influenza, SARS, Ebola, Hendra and Nipah viruses. Earlier this year three people became seriously ill and two of them died when they contracted a new SARS-like virus in the Middle East which is thought to have come directly from bats.

"Why bats harbour these viruses with limited ill effect is a mystery as the genetic make-up of these creatures is poorly understood. We are starting to apply our technique to laboratory grown bat cells to analyse the genetic and protein content of bats to gain more insight into their genetics and to understand how they are able to apparently co-exist with these viruses which all too often prove fatal in humans."

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The above story is reprinted from materials provided by University of Bristol, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Vanessa C Evans, Gary Barker, Kate J Heesom, Jun Fan, Conrad Bessant, David A Matthews. De novo derivation of proteomes from transcriptomes for transcript and protein identification. Nature Methods, 2012; DOI: 10.1038/nmeth.2227

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/VI0XgKra9e8/121111153926.htm

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Bahrain opposition leader: Hopes fading for talks

(AP) ? The head of Bahrain's main opposition group says envoys from the U.S. and other countries are acting as intermediaries with the Gulf nation's rulers, seeking to ease 21 months of unrest.

Sheik Ali Salman says there is little hope for breakthrough dialogue.

He also told The Associated Press on Sunday that Bahrain's main anti-government factions, including his Al Wefaq group, are unable to rein in breakaway protesters using increasingly violent tactics, including homemade firebombs.

Government officials also blame protesters for deadly explosions.

Bahrain's deepening crisis has led authorities to expand deployment of its paramilitary National Guard in the strategic nation, home to the U.S. Navy's 5th Fleet.

More than 55 people have been killed since February 2011 as majority Shiites seek a greater political voice in the Sunni-ruled kingdom.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-11-11-Bahrain/id-73b817d80fbb47529afb4c6ea19cd18e

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Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy

[ Back to EurekAlert! ] Public release date: 11-Nov-2012
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Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Latest in a series of groundbreaking discoveries

SEATTLE An international research team co-led by a scientist at Fred Hutchinson Cancer Research Center has identified two genetic factors behind the third most common form of muscular dystrophy. The findings, published online in Nature Genetics, represent the latest in the team's series of groundbreaking discoveries begun in 2010 regarding the genetic causes of facioscapulohumeral muscular dystrophy, or FSHD.

The team, co-led by Stephen Tapscott, M.D., Ph.D., a member of the Hutchinson Center's Human Biology Division, discovered that a rare variant of FSHD, called type 2, which accounts for about 5 percent of cases, is caused by two genetic mutations that together cause the production of muscle-damaging toxins responsible for causing symptoms of this progressive muscle disease.

Specifically, the researchers found that a combination of genetic variants on chromosomes 4 (called DUX4) and 18 (called SMCHD1) can cause type 2 FSHD. The DUX4 variant was first described by the research team in 2010 as a mechanism behind the more common, type 1, version of the disease.

"Many diseases caused by a single gene mutation have been identified during the last several decades, but it has been more difficult to identify the genetic basis of diseases that are caused by the intersection of multiple genetic flaws," Tapscott said. "Recent advances in DNA sequencing made this study possible and it is likely that other diseases caused by the inheritance of multiple genetic variants will be identified in the coming years." Understanding the genetic mechanisms of type 2 FSHD could lead to new biomarker-based tests for diagnosing the disease and could lead to the development of future treatments, Tapscott said.

FSHD affects about half a million people worldwide. Symptoms usually first appear around age 20 and are characterized by a progressive, gradual loss of muscle strength, particularly in the upper body.

###

In addition to Tapscott and other Hutchinson Center researchers, other key members of the research team included Daniel G. Miller, M.D., Ph.D., an associate professor of pediatrics at the University of Washington; Rabi N. Tawil, M.D., a professor of neurology at the University of Rochester Medical Center; and Silvre van der Maarel, Ph.D., a professor of medical epigenetics at Leiden University Medical Center in The Netherlands; plus investigators from Raboud University Nijmegen Medical Centre in The Netherlands and Nice University Hospital in France.

Funding for the research came from multiple institutions at the National Institutes of Health (National Institute of Neurological Disorders and Stroke, Clinical and Translational Science Awards Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Human Genome Research Institute and the National Genetics Institute), Friends of FSH Research, the Muscular Dystrophy Association, and the University of Rochester Medical Center Fields Center for FSHD and Neuromuscular Research.

At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Hutchinson Center's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, the Hutchinson Center houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Private contributions are essential for enabling Hutchinson Center scientists to explore novel research opportunities that lead to important medical breakthroughs. For more information visit www.fhcrc.org or follow the Hutchinson Center on Facebook, Twitter or YouTube.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 11-Nov-2012
[ | E-mail | Share Share ]

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
Fred Hutchinson Cancer Research Center

Latest in a series of groundbreaking discoveries

SEATTLE An international research team co-led by a scientist at Fred Hutchinson Cancer Research Center has identified two genetic factors behind the third most common form of muscular dystrophy. The findings, published online in Nature Genetics, represent the latest in the team's series of groundbreaking discoveries begun in 2010 regarding the genetic causes of facioscapulohumeral muscular dystrophy, or FSHD.

The team, co-led by Stephen Tapscott, M.D., Ph.D., a member of the Hutchinson Center's Human Biology Division, discovered that a rare variant of FSHD, called type 2, which accounts for about 5 percent of cases, is caused by two genetic mutations that together cause the production of muscle-damaging toxins responsible for causing symptoms of this progressive muscle disease.

Specifically, the researchers found that a combination of genetic variants on chromosomes 4 (called DUX4) and 18 (called SMCHD1) can cause type 2 FSHD. The DUX4 variant was first described by the research team in 2010 as a mechanism behind the more common, type 1, version of the disease.

"Many diseases caused by a single gene mutation have been identified during the last several decades, but it has been more difficult to identify the genetic basis of diseases that are caused by the intersection of multiple genetic flaws," Tapscott said. "Recent advances in DNA sequencing made this study possible and it is likely that other diseases caused by the inheritance of multiple genetic variants will be identified in the coming years." Understanding the genetic mechanisms of type 2 FSHD could lead to new biomarker-based tests for diagnosing the disease and could lead to the development of future treatments, Tapscott said.

FSHD affects about half a million people worldwide. Symptoms usually first appear around age 20 and are characterized by a progressive, gradual loss of muscle strength, particularly in the upper body.

###

In addition to Tapscott and other Hutchinson Center researchers, other key members of the research team included Daniel G. Miller, M.D., Ph.D., an associate professor of pediatrics at the University of Washington; Rabi N. Tawil, M.D., a professor of neurology at the University of Rochester Medical Center; and Silvre van der Maarel, Ph.D., a professor of medical epigenetics at Leiden University Medical Center in The Netherlands; plus investigators from Raboud University Nijmegen Medical Centre in The Netherlands and Nice University Hospital in France.

Funding for the research came from multiple institutions at the National Institutes of Health (National Institute of Neurological Disorders and Stroke, Clinical and Translational Science Awards Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Human Genome Research Institute and the National Genetics Institute), Friends of FSH Research, the Muscular Dystrophy Association, and the University of Rochester Medical Center Fields Center for FSHD and Neuromuscular Research.

At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. The Hutchinson Center's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, the Hutchinson Center houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Private contributions are essential for enabling Hutchinson Center scientists to explore novel research opportunities that lead to important medical breakthroughs. For more information visit www.fhcrc.org or follow the Hutchinson Center on Facebook, Twitter or YouTube.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-11/fhcr-rdt110812.php

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